Hepatitis A vaccine for post-exposure prophylaxis
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چکیده
Twenty-five contacts out of 568 (4.4%) who received the vaccine and 17 out of 522 contacts (3.3%) who received the immunoglobulin developed hepatitis A. The authors conclude that low rates of hepatitis A in both groups indicate that both interventions provided good protection after exposure. The slightly higher rates of hepatitis A among vaccine recipients may indicate a true difference in efficacy, which might be clinically important in some settings. Vaccine has other advantages including long term protection, and may be a reasonable alternative to immunoglobulin for postexposure prophylaxis in many circumstances. New England Journal of Medicine 2007; 357: 1685-94.
منابع مشابه
British HIV Association guidelines for immunization of HIV-infected adults 2008.
Table of contents 1.0 Introduction 1.1 General principles of immunization in HIVinfected adults 1.2 Practical aspects of immunization and general contraindication 2.0 Anthrax 2.1 Background 2.2 Epidemiology and risk groups 2.3 Anthrax vaccine 2.3.1 Vaccine efficacy 2.3.2 Vaccine safety 2.4 Recommendations for anthrax pre-exposure prophylaxis in HIV-infected adults 2.5 Post-exposure prophylaxis ...
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